Package: Roleswitch
Type: Package
Title: Infer miRNA-mRNA interactions using paired expression data from
        a single sample
Version: 1.2.0
Date: 2013-12-20
Author: Yue Li
Maintainer: Yue Li <yueli@cs.toronto.edu>
Description: Infer Probabilities of MiRNA-mRNA Interaction Signature
        (ProMISe) using paired expression data from a single sample.
        Roleswitch operates in two phases by inferring the probability
        of mRNA (miRNA) being the targets ("targets") of miRNA (mRNA),
        taking into account the expression of all of the mRNAs (miRNAs)
        due to their potential competition for the same miRNA (mRNA).
        Due to dynamic miRNA repression in the cell, Roleswitch assumes
        that the total transcribed mRNA levels are higher than the
        observed (equilibrium) mRNA levels and iteratively updates the
        total transcription of each mRNA targets based on the above
        inference. NB: in the paper, we used ProMISe as both the model
        name and inferred score name.
Depends: R (>= 2.10), pracma, reshape, plotrix, microRNA, biomaRt,
        Biostrings, Biobase, DBI
Suggests: ggplot2
License: GPL-2
URL: http://www.cs.utoronto.ca/~yueli/roleswitch.html
Lazyload: yes
biocViews: miRNA
Packaged: 2014-04-12 10:30:39 UTC; biocbuild
Built: R 3.1.0; ; 2014-04-12 16:39:39 UTC; windows
