Mutational Signature Estimation for Single Samples


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Documentation for package ‘SigsPack’ version 1.8.0

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bootstrap_mut_catalogues Bootstraps a given mutational catalogue
cosmicSigs COSMIC Signature Profiles
create_mut_catalogues Creates simulated mutational catalogues
decomposeQP decomposeQP function
get_context_freq Extract occurence of tri-nucleotide contexts
hg19context_freq Trinuecleotide frequencies of the human reference genome hg19
normalize Normalize mutational catalogues
plot_bootstrapped_exposure Plot signature exposure estimation for several samples
signature_exposure Estimates the signature exposure of a mutational catalogue
sigProfiler20190522 COSMIC v3 whole genome SBS Signature Profiles
sigProfilerExome COSMIC v3 exome SBS Signature Profiles
summarize_exposures Signature exposure analysis of a mutational catalogue
vcf2mut_cat Derive the mutational catalogue from a vcf