BUS-package {BUS} | R Documentation

## For network reconstruction.

### Description

This package can be used to compute associations among genes (gene-networks) or between genes and some external traits (i.e. clinical). [Function: BUS]

Both associations can be computed via correlation or mutual information (MI). [Functions: gene.similarity (gene-gene associations) and gene.trait.similarity (gene-trait associations)]

Statistical significance of the association is computed for single and multiple hypotheses testing, using random permutations method [Functions: gene.pvalue, gene.trait.pvalue]

The package can handle data with missing values using bootstrapping methods to fill NAs. [Arguments: na.replica]

### Details

Package: | BUS
Type: | Package
Version: | 1.0.2
Date: | 2009-10-31
License: | GPL-3

### Author(s)

Yin Jin, Hesen Peng, Lei Wang, Raffaele Fronza, Yuanhua Liu and Christine Nardini

Maintainer: Yuanhua Liu<liuyuanhua@picb.ac.cn.com>

[Package BUS version 1.50.0 Index]