orderedIntersect {GIGSEA} | R Documentation

## orderedIntersect

### Description

orderedIntersect sorts a data frame based on a given collumn and intersects with another vector.

### Usage

    orderedIntersect(x, by.x, by.y)

### Arguments

`x` | a data frame
`by.x` | a vector of character values. The data frame is sorted based on by.x
`by.y` | a vector of character values. After being sorted, the rows of x are further filtered by intersecting by.x with by.y

### Value

a data frame sorted by "by.x" and intersected with "by.y"

### Author(s)

Shijia Zhu, shijia.zhu@mssm.edu

### Examples

    # load data
    data(heart.metaXcan)
    gene <- heart.metaXcan$gene_name

    # extract the imputed Z-score of gene differential expression, which follows
    # normal distribution
    fc <- heart.metaXcan$zscore

    # use the prediction R^2 and fraction of imputation-used SNPs as weights
    usedFrac <- heart.metaXcan$n_snps_used / heart.metaXcan$n_snps_in_cov
    r2 <- heart.metaXcan$pred_perf_r2
    weights <- usedFrac*r2

    # build a new data frame for the following weighted linear regression-based
    # enrichment analysis
    data <- data.frame(gene,fc,weights)
    head(data)

    net <- MSigDB.KEGG.Pathway$net

    # intersect the user-provided imputed genes with the gene set of interest
    data2 <- orderedIntersect( x=data, by.x=data$gene, by.y=rownames(net) )
    net2 <- orderedIntersect( x=net, by.x=rownames(net), by.y=data$gene )
    all( rownames(net2) == as.character(data2$gene) )

[Package GIGSEA version 1.12.0 Index]