unlabel_data {HPiP} | R Documentation

## HP-PPIs with Unknown Class Labels

### Description

This dataset consists of interactions between SARS-CoV-2 and human proteins, achieved by AP-MS (affinity purification mass spectrometry).

### Usage

    data(unlabel_data)

### Format

A data.frame containing 700 SARS-CoV-2-Human protein-protein interactions (PPIs) with pre-computed numerical features using CTD (composition/transition/distribution) descriptors.

### Details

To construct this dataset, data (supplementary table 1) containing SARS-CoV-2-human PPIs was retrieved from (Gordon et al., 2020) and 700 pairs were randomly selected from total pairs, followed by converting protein sequences of host or viral proteins to numerical features and finally concatenating the computed features in order to construct host-pathogen PPIs.

### Source

https://www.nature.com/articles/s41586-020-2286-9#Sec36

### References

Gordon,D.E. et al. (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature, 583, 459–468.

[Package HPiP version 1.0.0 Index]