make_dnam_se {MethReg} | R Documentation

## Transform DNA methylation array into a summarized Experiment object

### Description

Transform DNA methylation array into a summarized Experiment object

### Usage

    make_dnam_se(
      dnam,
      genome = c("hg38", "hg19"),
      arrayType = c("450k", "EPIC"),
      betaToM = FALSE,
      verbose = FALSE
    )

### Arguments

`dnam` | DNA methylation matrix with beta-values or m-values as data, row as cpgs "cg07946458" or regions ("chr1:232:245") and column as samples
`genome` | Human genome of reference: hg38 or hg19
`arrayType` | DNA methylation array type (450k or EPIC)
`betaToM` | indicates if converting methylation beta values to mvalues
`verbose` | A logical argument indicating if messages output should be provided.

### Value

A summarized Experiment object with DNA methylation probes mapped to genomic regions

### Examples

    library(dplyr)
    dnam <- runif(20, min = 0,max = 1) %>% sort %>%
      matrix(ncol = 1) %>%  t
    rownames(dnam) <- c("chr3:203727581-203728580")
    colnames(dnam) <- paste0("Samples",1:20)
     se <- make_dnam_se(dnam)

[Package MethReg version 1.4.0 Index]