get_signed_ptms {OmnipathR} | R Documentation

## Signs for enzyme-substrate interactions

### Description

Enzyme-substrate data does not contain sign (activation/inhibition), we generate this information based on the interaction network.

### Usage

    get_signed_ptms(
      enzsub = import_omnipath_enzsub(),
      interactions = import_omnipath_interactions()
    )

### Arguments

`enzsub` | Enzyme-substrate data frame generated by `import_omnipath_enzsub`
`interactions` | interaction data frame generated by `import_omnipath_interactions`

### Value

Data frame of enzyme-substrate relationships with is_inhibition and is_stimulation columns.

### See Also

- `import_omnipath_enzsub`

- `import_omnipath_interactions`

### Examples

    enzsub <- import_omnipath_enzsub(resources = c('PhosphoSite', 'SIGNOR'))
    interactions <- import_omnipath_interactions()
    enzsub <- get_signed_ptms(enzsub, interactions)

[Package OmnipathR version 3.2.0 Index]