trrust_download {OmnipathR} | R Documentation

## Downloads TF-target interactions from TRRUST

### Description

TRRUST v2 (https://www.grnpedia.org/trrust/) is a database of literature mined TF-target interactions for human and mouse.

### Usage

    trrust_download(organism = "human")

### Arguments

`organism` | Character: either "human" or "mouse".

### Value

A data frame of TF-target interactions.

### Examples

    trrust_interactions <- trrust_download()
    trrust_interactions
    # # A tibble: 11,698 x 4
    #    source_genesymbol target_genesymbol effect reference
    #    <chr>             <chr>              <dbl> <chr>
    #  1 AATF              BAX                   -1 22909821
    #  2 AATF              CDKN1A                 0 17157788
    #  3 AATF              KLK3                   0 23146908
    #  4 AATF              MYC                    1 20549547
    #  5 AATF              TP53                   0 17157788
    #  6 ABL1              BAX                    1 11753601
    #  7 ABL1              BCL2                  -1 11753601
    # # . with 11,688 more rows

[Package OmnipathR version 3.2.0 Index]