poolCoverage {PureCN} | R Documentation

## Pool coverage from multiple samples

### Description

Averages the coverage of a list of samples.

### Usage

    poolCoverage(all.data, remove.chrs = c(), w = NULL)

### Arguments

`all.data` | List of normals, read with `readCoverageFile`.
`remove.chrs` | Remove these chromosomes from the pool.
`w` | `numeric(length(all.data))` vector of weights. If `NULL`, weight all samples equally.

### Value

A `data.frame` with the averaged coverage over all normals.

### Author(s)

Markus Riester

### See Also

`readCoverageFile`

### Examples

    normal.coverage.file <- system.file("extdata", "example_normal.txt",
        package = "PureCN")
    normal2.coverage.file <- system.file("extdata", "example_normal2.txt",
        package = "PureCN")
    normal.coverage.files <- c(normal.coverage.file, normal2.coverage.file)
    pool <- poolCoverage(lapply(normal.coverage.files, readCoverageFile),
         remove.chrs = c("chrX", "chrY"))

[Package PureCN version 2.0.2 Index]