initialize,RnBDiffMeth-method {RnBeads} | R Documentation

## initialize.RnBDiffMeth

### Description

Initialize an RnBDiffMeth object

### Usage

    ## S4 method for signature 'RnBDiffMeth'
    initialize(
      .Object,
      site.test.method = rnb.getOption("differential.site.test.method"),
      variability.method = rnb.getOption("differential.variability.method"),
      covg.thres = rnb.getOption("filtering.coverage.threshold"),
      disk.dump = FALSE,
      disk.path = NULL
    )

### Arguments

`.Object` | New instance of `RnBDiffMeth`.
`site.test.method` | method which was applied to obtain the site-level p-values.
`variability.method` | method to be used to calculate differentially variable sites. Has to be one of: ‘diffVar’ or ‘iEVORA’.
`covg.thres` | coverage threshold. Important for certain columns of the differential methylation tables. See `computeDiffMeth.bin.site` and `computeDiffMeth.bin.region` for details.
`disk.dump` | Flag indicating whether the tables should be stored on disk rather than in the main memory
`disk.path` | Path on the disk for DMTs.Only meaningful if `disk.dump` is `TRUE`

### Author(s)

Fabian Mueller

[Package RnBeads version 2.12.2 Index]