# Scalable Implementation of Generalized mixed models using GDS files in Phenome-Wide Association Studies

## Documentation for package ‘SAIGEgds’ version 1.8.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

SAIGEgds-package | Scalable Implementation of Generalized mixed models in Phenome-Wide Association Studies using GDS files
glmmHeritability | Heritability estimation
pACAT | Cauchy Combination Test
pACAT2 | Cauchy Combination Test
SAIGEgds | Scalable Implementation of Generalized mixed models in Phenome-Wide Association Studies using GDS files
seqAssocGLMM_SPA | P-value calculation
seqAssocGLMM_spaACAT_O | ACAT-V tests
seqAssocGLMM_spaACAT_V | ACAT-V tests
seqAssocGLMM_spaBurden | Burden tests
seqFitNullGLMM_SPA | Fit the null model with GRM
seqGLMM_GxG_spa | SNP Interaction Testing
seqSAIGE_LoadPval | Load the association results