mm_miR {TimiRGeN} | R Documentation

## Mouse microRNA data

### Description

Mouse Fibrosis microRNA data from differential expression analysis. Folic Acid was injected into mouse kidneys to induce fibrosis and nephropathy. Measurements were taken prior to (0 days) and 1, 2, 3, 7 and 14 after injection. The 0 time point was contrasted over other time points. Data was put through limma for analysis. mm_miR consists of DE results from 278 mouse miRs.

The miR names are using TimiRGeN friendly nomenclature. This data is an example of how miR names should be named before input into TimiRGeN.

Column names are in the following format: timepoint(days).DEresult (Log2FC or adjPVal).

### Usage

    data("mm_miR")

### Format

A data frame of miRNAs put through differential expression with 278 observations in the following 10 variables.

`D1.Log2FC`

  a numeric vector containing log2FC values of D1_fibrosis/ D0_fibrosis.

`D1.adjPVal`

  a numeric vector containing adjusted P values of D1_fibrosis/ D0_fibrosis.

`D2.Log2FC`

  a numeric vector containing log2FC values of D2_fibrosis/ D0_fibrosis.

`D2.adjPVal`

  a numeric vector containing adjusted P values of D2_fibrosis/ D0_fibrosis.

`D3.Log2FC`

  a numeric vector containing log2FC values of D3_fibrosis/ D0_fibrosis.

`D3.adjPVal`

  a numeric vector containing adjusted P values of D3_fibrosis/ D0_fibrosis.

`D7.Log2FC`

  a numeric vector containing log2FC values of D7_fibrosis/ D0_fibrosis.

`D7.adjPVal`

  a numeric vector containing adjusted P values of D7_fibrosis/ D0_fibrosis.

`D14.Log2FC`

  a numeric vector containing log2FC values of D14_fibrosis/ D0_fibrosis.

`D14.adjPVal`

  a numeric vector containing adjusted P values of D14_fibrosis/ D0_fibrosis.

### Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE613287

### References

M. Pavkovic, L. Pantano, C. V. Gerlach, S. Brutus, S. A. Boswell, R. A. Everley, J. V. Shah, S. H. Sui, and V. S. Vaidya, “Multi omics a nalysis of fibrotic kidneys in two mouse models,” Scientific data, vol. 6, no. 1, p. 92, 2019. <https://www.nature.com/articles/s41597-019-0095-5>

### Examples

    data(mm_miR)
    ## maybe str(mm_miR) ; plot(mm_miR) ...

[Package TimiRGeN version 1.4.0 Index]