svalue {apeglm} | R Documentation

## Local FSR to svalue

### Description

Convert local FSR to svalue by taking the cumulative mean of increasing local FSRs. This is used within `apeglm` to generate the svalue table, but provided as convenience function.

### Usage

    svalue(lfsr)

### Arguments

`lfsr` | the local false sign rates

### Value

s-values

### References

False sign rate and s-value:

Stephens, M. (2016) False discovery rates: a new deal. Biostatistics, 18:2. doi: 10.1093/biostatistics/kxw041

### Examples

    # Example 1 -- simulated local FSR data
    local.fsr <- runif(1000)
    sval <- svalue(local.fsr)

    # Example 2 -- first runs example from 'apeglm'
    example("apeglm")
    local.fsr <- res$fsr[1, ]
    sval <- svalue(local.fsr)

[Package apeglm version 1.16.0 Index]