effectiveLibSizes {edgeR} | R Documentation

## Effective Library Sizes

### Description

Extract effective (normalized) library sizes.

### Usage

    ## Default S3 method:
    effectiveLibSizes(y, log = FALSE, ...)

### Arguments

`y` | a object of class `DGEList`, `DGEGLM` or `DGELRT`. Alternatively a numeric matrix or an object that can be coerced to a numeric matrix.
`log` | logical, if `TRUE` then the library sizes are return on the natural log scale.
`...` | other arguments are not currently used.

### Details

This function extracts normalized library sizes, equal to the original library sizes multiplied by the corresponding normalization factors, from an edgeR data object or fitted model object.

If the object contains a row-specific offsets (i.e., a non-sparse matrix of offsets), then the offsets for the first row are returned.

### Value

A numeric matrix of effective (normalized) library sizes. If `log=TRUE`, then natural log values are returned, equal to library size offsets for a NB log-linear model.

### Author(s)

Gordon Smyth

### See Also

`calcNormFactors`

### Examples

    ngenes <- 100
    nsamples <- 4
    y <- DGEList(counts=matrix(rnbinom(ngenes*nsamples,size=1,mu=10),ngenes,nsamples))
    y <- calcNormFactors(y)
    data.frame(y$samples, eff.lib.size=effectiveLibSizes(y))

[Package edgeR version 3.36.0 Index]