LOCUS       ABD64816                1353 aa            linear   INV 12-MAR-2006
DEFINITION  Egfr, partial [Drosophila virilis].
ACCESSION   ABD64816
VERSION     ABD64816.1  GI:89243303
DBSOURCE    accession DQ378290.1
KEYWORDS    .
SOURCE      Drosophila virilis
  ORGANISM  Drosophila virilis
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
REFERENCE   1  (residues 1 to 1353)
  AUTHORS   Slawson,E.E., Shaffer,C.D., Malone,C.D., Leung,W., Kellmann,E.,
            Shevchek,R.B., Craig,C.A., Bloom,S.M., Bogenpohl,J. II, Dee,J.,
            Morimoto,E.T., Myoung,J., Nett,A.S., Ozsolak,F., Tittiger,M.E.,
            Zeug,A., Pardue,M.L., Buhler,J., Mardis,E.R. and Elgin,S.C.
  TITLE     Comparison of dot chromosome sequences from D. melanogaster and D.
            virilis reveals an enrichment of DNA transposon sequences in
            heterochromatic domains
  JOURNAL   Genome Biol. 7 (2), R15 (2006)
   PUBMED   16507169
REFERENCE   2  (residues 1 to 1353)
  AUTHORS   Slawson,E.E., Shaffer,C.D., Malone,C.D., Leung,W., Kellmann,E.,
            Shevchek,R.B., Craig,C.A., Bloom,S.M., Bogenpohl,J. II, Dee,J.,
            Morimoto,E.T.A., Myoung,J., Nett,A.S., Ozsolak,F., Tittiger,M.E.,
            Zeug,A., Pardue,M.-L., Buhler,J., Mardis,E.R. and Elgin,S.C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2006) Biology Department, Washington University,
            One Brookings Drive, St. Louis, MO 63130, USA
COMMENT     Method: conceptual translation supplied by author.
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Drosophila virilis"
                     /strain="Tucson 15010-1001.10"
                     /db_xref="taxon:7244"
                     /clone="fosmid 10J19"
                     /clone_lib="fosmids from BACPAC Center at CHORI"
                     /note="contig 112; part of a major chromosome; not
                     chromosome 4"
     Protein         <1..1353
                     /product="Egfr"
                     /name="Dvir_CG10079"
     Region          27..138
                     /region_name="Recep_L_domain"
                     /note="Receptor L domain; pfam01030"
                     /db_xref="CDD:250307"
     Region          156..304
                     /region_name="Furin-like"
                     /note="Furin-like cysteine rich region; pfam00757"
                     /db_xref="CDD:250112"
     Region          203..246
                     /region_name="FU"
                     /note="Furin-like repeats. Cysteine rich region. Exact
                     function of the domain is not known. Furin is a
                     serine-kinase dependent proprotein processor. Other
                     members of this family include endoproteases and cell
                     surface receptors; cd00064"
                     /db_xref="CDD:238021"
     Region          320..446
                     /region_name="Recep_L_domain"
                     /note="Receptor L domain; pfam01030"
                     /db_xref="CDD:250307"
     Region          473..585
                     /region_name="GF_recep_IV"
                     /note="Growth factor receptor domain IV; pfam14843"
                     /db_xref="CDD:258980"
     Region          474..522
                     /region_name="FU"
                     /note="Furin-like repeats. Cysteine rich region. Exact
                     function of the domain is not known. Furin is a
                     serine-kinase dependent proprotein processor. Other
                     members of this family include endoproteases and cell
                     surface receptors; cd00064"
                     /db_xref="CDD:238021"
     Region          523..570
                     /region_name="FU"
                     /note="Furin-like repeats. Cysteine rich region. Exact
                     function of the domain is not known. Furin is a
                     serine-kinase dependent proprotein processor. Other
                     members of this family include endoproteases and cell
                     surface receptors; cd00064"
                     /db_xref="CDD:238021"
     Region          640..687
                     /region_name="FU"
                     /note="Furin-like repeats. Cysteine rich region. Exact
                     function of the domain is not known. Furin is a
                     serine-kinase dependent proprotein processor. Other
                     members of this family include endoproteases and cell
                     surface receptors; cd00064"
                     /db_xref="CDD:238021"
     Region          689..>734
                     /region_name="FU"
                     /note="Furin-like repeats. Cysteine rich region. Exact
                     function of the domain is not known. Furin is a
                     serine-kinase dependent proprotein processor. Other
                     members of this family include endoproteases and cell
                     surface receptors; cd00064"
                     /db_xref="CDD:238021"
     Region          829..1107
                     /region_name="PTKc_EGFR_like"
                     /note="Catalytic domain of Epidermal Growth Factor
                     Receptor-like Protein Tyrosine Kinases; cd05057"
                     /db_xref="CDD:270648"
     Region          837..1093
                     /region_name="Pkinase_Tyr"
                     /note="Protein tyrosine kinase; pfam07714"
                     /db_xref="CDD:254379"
     Site            order(843..844,847..848,870,916,918,922,966..967,980,
                     1001..1005,1010,1014)
                     /site_type="active"
                     /db_xref="CDD:270648"
     Site            order(843..844,851,868,870,891,915..916,918,966..967,969,
                     980)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270648"
     Site            979..1004
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270648"
     Site            order(1001..1005,1010,1014)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270648"
     CDS             1..1353
                     /gene="Egfr"
                     /locus_tag="EDV_Mg0013"
                     /gene_synonym="Dvir\CG10079"
                     /coded_by="complement(join(DQ378290.1:21315..23841,
                     DQ378290.1:23907..24039,DQ378290.1:24104..25284,
                     DQ378290.1:25364..>25586))"
                     /codon_start=3
ORIGIN      
        1 cigtksrlsv psnrdhhyrn lrdrytncty vdgnleltwl qdpnldlsfl anirevtgyi
       61 lishvdvtkv ifpklqiirg rtlfsltvde akyalfaays kmntlempel rdilqgwvgf
      121 fsnynlchtr sivwreilsg vndhynytyn ftaeertcpk cdpscergac wgegphncqk
      181 fskincapqc aqgrcfgqgp rdcchlfcag gctgptqkdc iacknffddg vckeecppmr
      241 kynptnyele anpegkyayg atcvrecpgh llkdngacvr scpsdkmakd gecvacngpc
      301 pktcpgvpvl nsgnidsfkn ctviegnirv ldqtfsgyqd insnytmgar yipmhpdrle
      361 vfstvkeitg ylniegvhqh fknlsyfrnl evihgrqlme sffaalsivk sslsslelrn
      421 lkrinsgsiv iqhneklcyv snirwstvqk sndqmqyine nlntsecrka rqvcsdqcns
      481 dgcwgagpdq clncksfnyn gtciadcrnv tktyqfdakt ckkchpecrt csgpgaehcd
      541 ecvhvrddqh cvtvcpenky sdfgicrrch etcegctgpn ntighgacnt cnlaiinada
      601 tverclrkdd kcpdgyywey vhpqeqgslk plagkaicrk chprcelctn ygfheqvcsk
      661 cagykrreqc edecpadhya deekrecfec hpeckgctgp gsedclacrn fklfaesevy
      721 dnstlfncts kcppelphvn yqshfigphc asspprgskl taglnvnmii iifvavfipv
      781 icvlcviiyi crqkqqekke tddlakvffg cedseplrps niganlsklr ivkdaelrkg
      841 gvlgmgafgr vykgvwvpeg envkipvaik ellktsgaes sqeflneaya matvehgnll
      901 kllavcmssq mmlitqlmpl gclldyvrnn rdkigskall nwstqiakgm syleerrlvh
      961 rdlaarnvlv qtpslvkitd fglakllsld sneykaaggk mpikwlalec irhrvfssks
     1021 dvwafgvtiw elltfgqrph enilakdipd liemglkleq peicsldiyc tllscwqlda
     1081 dlrppfkqlt nvfaefardp grylaipgdk ftrlpaytsq dekdlirkla pttdgsepmv
     1141 eaddylqpka apgpshrtdg tdeipklnry ckdpsnknsn sggiggddet dsnarevgvg
     1201 nlrldlpvde ddylmptgqg npngnnnnnn nnsnnpnnnm ataaatgyid vigvskrwey
     1261 ikqantnpil alshnqvpvs vdnpeyllna lsageapmpt qtigipvagv pgtmevkmpg
     1321 sestssdhey yndtqrelqp lqllrsrste trv
//

