mirData {isomiRs} | R Documentation

## Example of IsomirDataSeq with human brain miRNA counts data

### Description

This data set is the object return by `IsomirDataSeqFromFiles`. It contains miRNA count data from 14 samples: 7 control individuals (pc) and 7 patients with Parkinson's disease in early stage (Pantano et al, 2016). Use `colData` to see the experiment design.

### Usage

    data("mirData")

### Format

a `IsomirDataSeq` class.

### Author(s)

Lorena Pantano, 2018-04-27

### Source

Data is available from GEO dataset under accession number GSE97285

Every sample was analyzed with seqbuster tool, see http://seqcluster.readthedocs.org/mirna_annotation.html for more details. You can get same files running the small RNA-seq pipeline from https://github.com/bcbio/bcbio-nextgen.

bcbio_nextgen was used for the full analysis.

See `raw-data.R` to know how to recreate the object. This script is inside "extra" folder of the package.

### References

Pantano L, Friedlander MR, Escaramis G, Lizano E et al. Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis. Bioinformatics 2016 Mar 1;32(5):673-81. PMID: 26530722

[Package isomiRs version 1.22.1 Index]