.methylcc_mstep {methylCC} | R Documentation

## Maximization step

### Description

Maximization step in EM Algorithm for methylCC

### Usage

    .methylcc_mstep(Ys, Zs, current_pi_mle, current_theta, estep0, estep1)

### Arguments

`Ys` | observed methylation levels in samples provided by user of dimension R x n
`Zs` | Cell type specific regions of dimension R x K
`current_pi_mle` | cell composition MLE estimates of dimension K x n
`current_theta` | other parameter estimates in EM algorithm
`estep0` | Results from expectation step for unmethylated regions
`estep1` | Results from expectation step for methylated regions

### Value

A list of the updated MLEs (or the M-Step in the EM algorithm) used in `.methylcc_engine()`

[Package methylCC version 1.8.0 Index]