methylation_specificity {spiky} | R Documentation

## compute methylation specificity for spike-in standards

### Description

In a cfMeDIP experiment, the yield of methylated fragments should be >95% (ideally 98-99%) due to the nature of the assay.

### Usage

    methylation_specificity(ssb_res, spike)

### Arguments

`ssb_res` | output object from scan_spiked_bam
`spike` | spike contig database, if needed (e.g. data(spike))

### Value

             list with median and mean coverage across spike contigs

### Examples

    data(ssb_res)
    data(spike, package="spiky")
    methylation_specificity(ssb_res,spike=spike)

[Package spiky version 1.0.0 Index]