omimIds {goProfiles} | R Documentation |
Entrez identifiers for several lists of genes related with human disease.
diseaseIds
morbidmapIds
dominantIds
recessiveIds
dominantIdsEBI
recessiveIdsEBI
dominantIdsNCBI
recessiveIdsNCBI
data(omimIds)
Each dataset is a character vector with a different number of elements which (should) correspond to valid Entrez identifiers
Lopez-Bigas et al. analyzed the distribution of functional categories in genes causing disease in human.
They did several comparisosn which can also be done using goProfiles
. In order to perform these comparisons
we first tried to obtain the same lists of genes using standard database browsers, such as 'SRS', at the European Bioinformatics Institute, or 'Entrez', at the National Center for Biotechnological Information. Curiously both approaches provided very different lists so we asked the authors for their data and they kindly provided them to us. In order to facilitat the use of functions included in goProfiles
we have trimmed the list of recessive and dominant genes so that (i) They become exclussive (no gene belows to both lists) (2) They are both included in the diseaseIds
list. This eliminated 39 genes (out of 639) from the list of recessive genes and 52 genes (out of 414) from the list of dominant genes
Lopez-Bigas, N., Blencowe, B.J. and Ouzounis, C.A., Highly consistent patterns for inherited human diseases at the molecular level, Bioinformatics, 2006, 22 (3), 269-277.
data(omimIds)