metaprep-class {metahdep} | R Documentation |
This is a class representation for the effect size estimates and other summary information for a single gene, from a collection of gene expression studies, usually constructed in preparation for a meta-analysis.
Objects can be created using the function metahdep.format
and new
.
theta
:vector
representing the gene's effect size estimates (differential expression measures) from the multiple studies. V
:matrix
representing the sampling variance/covariance matrix of the gene's effect size estimates from the multiple studies. X
:matrix
representing the covariate (or design) matrix for the gene. Covariate information from the multiple studies is represented here. M
:matrix
representing the block diagonal hierarchical structure of effect size estimates from the multiple studies. max.k
:integer
representing the size of the largest block on the diagonal of M
, i.e., the size of the largest hierarchical dependence group for the gene. row.indices
:matrix
with columns named Study and Row. Optionally returned by the function metahdep.format()
, to see which gene (Row) in which ES.obj
object (Study) produced the data recorded in each metaprep
object. gene
:character
representing the gene name. ### ### See the metahdep package vignette for a full example ### data(HGU.prep.list) HGU.prep.list[[7]]