sim.intervention {nem} | R Documentation |
Simulates a knock-down of a list of network nodes and returns the network nodes and effect reporters, where effects are expected.
sim.intervention(x, int)
x |
nem object |
int |
a character vector of nodes in the network |
list with two slots:
Sgenes.effected |
effected network nodes |
Egenes.effected |
effected downstream effect reporters |
Holger Froehlich
data("BoutrosRNAi2002") D <- BoutrosRNAiDiscrete[,9:16] res = nem(D, control=set.default.parameters(unique(colnames(D)), para=c(0.13,0.05))) sim.intervention(res, "rel") # simulate knock-down of rel