sFiltert {CLL} | R Documentation

## Boolean values for specific filtering based on the t-test

### Description

sFiltert is a named vector of booleans indicating whether a gene passed the specific and non-specific filtering steps. The specific filtering was to perform row t-tests and a TRUE value was obtained if the p-value was less than 0.005. So to have a TRUE value in sFiltert, the gene must have a row t-test p-value less than 0.005, an interquartile range of at least 0.5 on the log2 scale, and at least 25% of the samples had an expression value greater than 100 on the normal scale (the last 2 criteria were the nonspecific filters).

A TRUE value indicates that the gene passed the filtering step and should be included in further analysis.

### Usage

    data(sFiltert)

### Format

A named vector of logicals. The names correspond to the Affymetrix identifiers and the values are booleans indicating whether the gene passed the nonspecific and specific filtering (based on t-test p-values).

### Source

The CLL microarray data came from Dr. Sabina Chiaretti at Division of Hematology, Department of Cellular Biotechnologies and Hematology, University La Sapienza, Rome, Italy and Dr. Jerome Ritz at Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

### Examples

    data(sFiltert)
    data(sCLLex)
    sCLLexSF<-sCLLex[sFiltert, ]

[Package CLL version 1.2.0 Index]