inputCaseC {GRmetrics} | R Documentation

## Simulated dose-response assay data (Case C)

### Description

This is an example dataset corresponding to Case C. The dataset is equivalent to that of Case A, but in a different form. The data was generated by the python script "generate_data.py" found in the "inst/scripts/" directory. This object is meant to be used as the "inputData" argument for the `GRfit` function when "case" is equal to "C". The input data for "Case C" of the `GRfit` function must be in this format with columns named "concentration", "cell_count", and "time" as well as columns for other key variables. The columns "cell_line", "agent", "perturbation", and "replicate", are simply examples of these key variables. It is not necessary that your input data frame include these exact column names or the same number of columns.

### Usage

    inputCaseC

### Format

A data frame with 1352 rows and 7 variables:

- cell_line: the cell-line used (MCF10A, MCF7, BT20)

- agent: the drug used (-, drugA, drugB, drugC, drugD)

- pertubation: an example of another key variable (e.g different media, a co-treatment, etc.) (0, 1)

- replicate: replicate number, (1, 2, 3)

- time: time of assay measured in hours (0, 48, 72)

- concentration: concentration of the perturbagen on which dose-response curves will be evaluated (not log transformed)

- cell_count: measure of cell number or a surrogate of the number of cells.

### Value

An example dataset in the form of "Case C" generated for use with `GRfit`

### Source

inst/scripts/generate_data.py

[Package GRmetrics version 1.8.1 Index]