relationsMeanVar {GWASTools} | R Documentation

## Mean and Variance information for full-sibs, half-sibs, first-cousins

### Description

Computes theoretical mean and covariance matrix for k0 vs. k1 ibd coefficients for full-sib relationship along with inverse and eigenvalues/vectors of the covariance matrix.

Computes theoretical means and variances for half-sib relationship and for first-cousin relationship.

### Usage

    relationsMeanVar

### Format

A list with the following entries:

`FullSibs`

  list with following entries:

  - `mean`: mean of (k0,k1) for full-sibs

  - `cov`: covariance matrix for full-sibs

  - `invCov`: inverse of the covariance matrix

  - `eigvals`: eigenvalues of the inverse covariance matrix

  - `eigvectors`: eigenvectors of the inverse covariance matrix

`HalfSibs`

  list with following entries:

  - `mean`: mean of (k0,k1) for half-sibs

  - `var`: variance for half-sibs

`FirstCousins`

  list with following entries:

  - `mean`: mean of (k0,k1) for first-cousins

  - `var`: variance for first-cousin

### Source

computed by Cecelia Laurie using the referenced papers

### References

Hill, W.G. and B.S. Weir (2011) Variation in actual relationship as a consequence of Mendelian sampling and linkage,Genet. Res., Camb., 93, 47–64.

Kong, X., et al (2004) A combined physical-linkage map of the human genome, American Journal of Human Genetics, 75, 1143–1148.

### Examples

    data(relationsMeanVar)
    FS<-relationsMeanVar$FullSibs
    FScov<-FS$cov   #gives covariance matrix for full-sibs
    HS<-relationsMeanVar$HalfSibs
    HSvar<-HS$var  #gives variance for half-sibs

[Package GWASTools version 1.28.0 Index]