TPP {TPP} | R Documentation

## Thermal proteome profiling (TPP)

### Description

TPP is a toolbox for analyzing thermal proteome profiling (TPP) experiments.

### Usage

    .onLoad(libname, pkgname)

### Arguments

`libname` | a character string giving the library directory where the package defining the namespace was found. Passed to .onLoad function.
`pkgname` | a character string giving the name of the package. Passed to .onLoad function.

### Details

In order to start a TPP-TR analysis, use function `analyzeTPPTR`. For a TPP-CCR analysis, use function `analyzeTPPCCR`. See the vignette for detailed instructions.

### Value

No return value defined for this document.

### References

Savitski, M. M., Reinhard, F. B., Franken, H., Werner, T., Savitski, M. F., Eberhard, D., ... & Drewes, G. (2014). Tracking cancer drugs in living cells by thermal profiling of the proteome. Science, 346(6205), 1255784.

Franken, H, Mathieson, T, Childs, D. Sweetman, G. Werner, T. Huber, W. & Savitski, M. M. (2015), Thermal proteome profiling for unbiased identification of drug targets and detection of downstream effectors. Nature protocols 10(10), 1567-1593.

[Package TPP version 3.10.1 Index]