bdfunc.enrichment.human {sRAP} | R Documentation

## BD-Func Enrichment File for Human Gene Symbols

### Description

Contains genes lists of paired up-regulated and down-regulated genes. Gene Lists come from Gene Ontology (GO [1]) and MSigDB [2].

BD-Func [3] will compare the expression patterns for the up-regulated genes to the down-regulated genes.

### Usage

    data(bdfunc.enrichment.human)

### Source

GO Gene Lists: http://www.geneontology.org/GO.downloads.annotations.shtml MSigDB Gene Lists: http://www.broadinstitute.org/gsea/downloads.jsp

### References

[1] Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM, and Sherlock G.(2000). Gene Ontology: tool for the unification of biology Nat Genet, 25:25-29

[2] Liberzon A, Subramanian A, Pinchback R, Thorvaldsdottir H, Tamayo P, and Mesirov JP.(2011). Molecular signatures database (MSigDB) 3.0. Bioinformatics, 27:1739-1740.

[3] Warden CD, Kanaya N, Chen S, and Yuan Y-C. (2013). BD-Func: A Streamlined Algorithm for Predicting Activation and Inhibition of Pathways. peerJ, 1:e159

[Package sRAP version 1.22.0 Index]