combination_index {MACSQuantifyR} | R Documentation

## compute combination index

### Description

This function allows the user to compute combination index on the drug combinations. This function also generates intermediary plots and tables.

### Usage

    combination_index(MACSQuant, ...)

### Arguments

`MACSQuant` | object of class MACSQuant resulting of the function load_maxQuant(). Contains the original data table
`...` | params for lattice cloud namely z and x for parameter screen default for z and x are c(-110,-70) and argument xlab and ylab

### Value

Several plots and combination index

### References

Chou, T. C. (2006). Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacological reviews, 58(3), 621-681.

### Examples

    filepath <- system.file("extdata", "drugs.Rdata",
        package = "MACSQuantifyR")
    load(filepath)
    combination_index(MACSQuant)

[Package MACSQuantifyR version 1.0.1 Index]