lrTestBias {PathwaySplice} | R Documentation

## lrTestBias

### Description

This function tests presence of selection bias using logistic regression, and produces a boxplot that compares distributions of bias factors (e.g. number of exons) for significant genes and non-significant genes.

### Usage

    lrTestBias(genewise.table, boxplot.width = 0.1)

### Arguments

`genewise.table` | A dataframe with genewise p-value for each gene, returned from `makeGeneTable()`
`boxplot.width` | width of boxplot

### Details

To determine presentce of selection bias, we fit the following logistic regression model:

`Pr(a gene is significant) ~ number of features within the gene`

Here features refer to exon bins or splicing junction bins, depending on how genewise pvalues were obtained in the `genewise.table`

### Value

Nothing to be returned

### Examples

    gene.based.table <- makeGeneTable(featureBasedData)
    lrTestBias(gene.based.table)

[Package PathwaySplice version 1.10.0 Index]