disaggregate {SWATH2stats} | R Documentation

## Transforms the SWATH data from a peptide- to a transition-level table.

### Description

If the SWATH data should be analyzed on transition-level the data needs to be tranformed from peptide-level table to a transition-level table (one row per transition instead of one row per peptide). The columns "aggr_Fragment_Annotation" and "aggr_Peak_Area" are disaggregated into the new columns "Fragmentation" and "Intensity". The following columns are renamed if they exist: FullPeptideName -> PeptideSequence, Charge -> PrecursorCharge, Area -> Intensity, Fragment -> Fragmentation, Sequence -> NakedSequence.

### Usage

    disaggregate(data, all.columns = FALSE)

### Arguments

`data` | A data frame containing SWATH data.
`all.columns` | Option that all columns are processed. Otherwise only the columns typically needed for downstream analysis are processed.

### Value

Returns a data frame containing the SWATH data in a transition-level table.

### Author(s)

Peter Blattmann

### Examples

    {
     data("OpenSWATH_data", package="SWATH2stats")
     data("Study_design", package="SWATH2stats")
     data <- sample_annotation(OpenSWATH_data, Study_design)
     data.filtered.decoy <- filter_mscore(data, 0.01)
     raw <- disaggregate(data.filtered.decoy)
     }

[Package SWATH2stats version 1.20.1 Index]