RA_100samples {TOAST} | R Documentation

## An example dataset for cellular proportion estimation and multiple factor design

### Description

The dataset contains normalized beta valutes for 3000 CpGs from 100 samples (50 Rheumatoid arthritis patients and 50 controls) and their phenotypes (disease status, age, and gender). The dataset also contains a sub-setted blood reference matrix for the matched 3000 CpGs. This data was obtained and processed based on GSE42861.

### Usage

    data("RA_100samples")

### References

Liu Y, Aryee MJ, Padyukov L, Fallin MD et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol 2013 Feb;31(2):142-7. PMID: 23334450

### Examples

    data(RA_100samples)
    RA_100samples$Y_raw[1:5,1:5]
    head(RA_100samples$Pheno)
    head(RA_100samples$Blood_ref)

[Package TOAST version 1.4.0 Index]