| add_flank_to_variants | Uses a genome object to find context and add it to the variant table |
| annotate_replication_strand | Add replication strand annotation to SBS variants based on bedgraph file |
| annotate_transcript_strand | Add transcript strand annotation to SBS variants (defined in genes only) |
| annotate_variant_length | Adds an annotation to the input musica's variant table with length of each variant |
| annotate_variant_type | Annotate variants with variant type ("SBS", "INS", "DEl", "DBS") |
| auto_predict_grid | Automatic filtering of signatures for exposure prediction gridded across specific annotation |
| build_custom_table | Builds a custom table from specified user variants |
| build_standard_table | Builds count tables using various mutation type schemas |
| built_tables | Retrieve the names of count_tables from a musica or musica_result object |
| built_tables-method | Retrieve the names of count_tables from a musica or musica_result object |
| cluster_exposure | Perform clustering analysis from a musica result object |
| combine_count_tables | Combines tables into a single table that can be used for discovery/prediction |
| combine_predict_grid | Combine prediction grid list into a result object. Exposure values are zero for samples in an annotation where that signature was not predicted |
| compare_cosmic_v2 | Compare a result object to COSMIC V2 SBS Signatures (combination whole-exome and whole-genome) |
| compare_cosmic_v3 | Compare a result object to COSMIC V3 Signatures; Select exome or genome for SBS and only genome for DBS or Indel classes |
| compare_results | Compare two result files to find similar signatures |
| cosmic_v2_sigs | COSMIC v2 SBS96 Signatures Result Object |
| cosmic_v2_subtype_map | Input a cancer subtype to return a list of related COSMIC signatures |
| cosmic_v3_dbs_sigs | COSMIC v3 DBS Genome Signatures Result Object |
| cosmic_v3_indel_sigs | COSMIC v3 Indel Genome Signatures Result Object |
| cosmic_v3_sbs_sigs | COSMIC v3 SBS96 Genome Signatures Result Object |
| cosmic_v3_sbs_sigs_exome | COSMIC v3 SBS96 Exome Signatures Result Object |
| count_table-class | Object containing the count table matrices, their names and descriptions that we generated by provided and by user functions. These are used to discover and infer signatures and exposures. |
| create_musica | Creates a musica object from a variant table |
| create_umap | Create a UMAP from a musica result |
| dbs_musica | dbs_musica |
| discover_signatures | Discover mutational signatures |
| drop_annotation | Drops a column from the variant table that the user no longer needs |
| exposures | Retrieve exposures from a musica_result object |
| exposures-method | Retrieve exposures from a musica_result object |
| exposures<- | Retrieve exposures from a musica_result object |
| exposures<--method | Retrieve exposures from a musica_result object |
| exposure_differential_analysis | Compare exposures of annotated samples |
| extract_count_tables | Extract count tables list from a musica object |
| extract_variants | Extract variants from mutliple objects |
| extract_variants_from_maf | Extract variants from a maf object |
| extract_variants_from_maf_file | Extracts variants from a maf file |
| extract_variants_from_matrix | Extract variants from matrix or data.frame like objects |
| extract_variants_from_vcf | Extracts variants from a VariantAnnotation VCF object |
| extract_variants_from_vcf_file | Extracts variants from a vcf file |
| generate_result_grid | Generate result_grid from musica based on annotation and range of k |
| get_musica | Retrieve musica from a musica_result object |
| get_musica-method | Retrieve musica from a musica_result object |
| indel_musica | indel_musica |
| k_select | Plots for helping decide number of clusters |
| musica | musica |
| musica-class | The primary object that contains variants, count_tables, and samples annotations |
| musicatk | Starts the musicatk interactive Shiny app |
| musica_annot | musica_annot |
| musica_result-class | Object containing deconvolved/predicted signatures, sample weights, and the musica object the result was generated from |
| musica_result_grid-class | Object containing the result objects generated from the combination of annotations and a range of k values |
| musica_sbs96 | musica_sbs96 |
| musica_sbs96_tiny | musica_sbs96_tiny |
| name_signatures | Return sample from musica object |
| plot_cluster | Visualize clustering results |
| plot_differential_analysis | Compare exposures of annotated samples |
| plot_exposures | Display sample exposures with bar, box, or violin plots |
| plot_heatmap | Plot heatmaps using the exposures matrix |
| plot_sample_counts | Plot distribution of sample counts |
| plot_sample_reconstruction_error | Plot reconstruction error for a sample |
| plot_signatures | Plots the mutational signatures |
| plot_umap | Plot a UMAP from a musica result |
| predict_exposure | Prediction of exposures in new samples using pre-existing signatures |
| rc | Reverse complement of a string using biostrings |
| rep_range | Replication Timing Data as GRanges Object |
| res | res |
| res_annot | res_annot |
| sample_names | Retrieve sample names from a musica or musica_result object |
| sample_names-method | Retrieve sample names from a musica or musica_result object |
| samp_annot | Get or set sample annotations from a musica or musica_result object |
| samp_annot-method | Get or set sample annotations from a musica or musica_result object |
| samp_annot<- | Get or set sample annotations from a musica or musica_result object |
| samp_annot<--method | Get or set sample annotations from a musica or musica_result object |
| select_genome | Helper function to load common human or mouse genomes |
| signatures | Retrieve signatures from a musica_result object |
| signatures-method | Retrieve signatures from a musica_result object |
| signatures<- | Retrieve signatures from a musica_result object |
| signatures<--method | Retrieve signatures from a musica_result object |
| subset_musica_by_annotation | Creates a new musica object subsetted to only one value of a sample annotation |
| subset_musica_by_counts | Creates a new musica subsetted to only samples with enough variants |
| subset_variants_by_samples | Return sample from musica_variant object |
| subset_variant_by_type | Subsets a variant table based on Variant Type |
| tables | Retrieve the list of count_tables from a musica or musica_result object |
| tables-method | Retrieve the list of count_tables from a musica or musica_result object |
| tables<- | Retrieve the list of count_tables from a musica or musica_result object |
| tables<--method | Retrieve the list of count_tables from a musica or musica_result object |
| table_selected | Retrieve table name used for plotting from a musica_result object |
| table_selected-method | Retrieve table name used for plotting from a musica_result object |
| umap | Retrieve umap list from a musica_result object |
| umap-method | Retrieve umap list from a musica_result object |
| umap<- | Retrieve umap list from a musica_result object |
| umap<--method | Retrieve umap list from a musica_result object |
| variants | Retrieve variants from a musica or musica_result object |
| variants-method | Retrieve variants from a musica or musica_result object |
| variants<- | Retrieve variants from a musica or musica_result object |
| variants<--method | Retrieve variants from a musica or musica_result object |