Package: AUCell
Type: Package
Title: AUCell: Analysis of 'gene set' activity in single-cell RNA-seq
        data (e.g. identify cells with specific gene signatures)
Version: 1.0.0
Date: 2017-09-26
Author: Sara Aibar, Stein Aerts. Laboratory of Computational Biology. VIB-KU
    Leuven Center for Brain & Disease Research. Leuven, Belgium
Maintainer: Sara Aibar <sara.aibar@kuleuven.vib.be>
Description: AUCell allows to identify cells with active gene sets 
    (e.g. signatures, gene modules...) in single-cell RNA-seq data. 
    AUCell uses the "Area Under the Curve" (AUC) to calculate whether a critical 
    subset of the input gene set is enriched within the expressed genes for each cell. 
    The distribution of AUC scores across all the cells allows exploring the 
    relative expression of the signature. Since the scoring method is ranking-based, 
    AUCell is independent of the gene expression units and the normalization procedure.
    In addition, since the cells are evaluated individually, it can easily be 
    applied to bigger datasets, subsetting the expression matrix if needed. 
URL: http://scenic.aertslab.org
Imports: R.utils, utils, graphics, stats, data.table, mixtools,
        GSEABase, SummarizedExperiment, methods
Enhances: doMC, doRNG, doParallel, foreach
Suggests: Biobase, GEOquery, devtools, zoo, DT, NMF, plotly, BiocStyle,
        knitr, rmarkdown, testthat
License: GPL-3
biocViews: SingleCell, GeneSetEnrichment, Transcriptomics,
        Transcription, GeneExpression, WorkflowStep, Normalization
LazyData: TRUE
VignetteBuilder: knitr
RoxygenNote: 6.0.1
NeedsCompilation: no
Packaged: 2017-10-31 02:21:44 UTC; biocbuild
Built: R 3.4.2; ; 2017-10-31 02:58:28 UTC; windows
