wrapper.normalizeD {DAPAR} | R Documentation

## Normalization

### Description

Provides several methods to normalize quantitative data from a `MSnSet` object. They are organized in four main families : Global Alignment, Median Centering, Mean Centering, Mean Centering Scaling. For the first family, two sub-categories are available : the sum by columns and the quantiles method. For the three other families, two categories are available : "Overall" which means that the value for each protein (ie line in the expression data tab) is computed over all the samples ; "within conditions" which means that the value for each protein (ie line in the `exprs()` data tab) is computed condition by condition.

### Usage

    wrapper.normalizeD(obj, family, method)

### Arguments

`obj` | An object of class `MSnSet`.
`family` | One of the following : Global Alignment, Median Centering, Mean Centering, Mean Centering Scaling.
`method` | "overall" or "within conditions".

### Value

An instance of class `MSnSet` where the quantitative data in the `exprs()` tab has been normalized.

### Author(s)

Alexia Dorffer

### Examples

    require(DAPARdata)
    data(Exp1_R25_pept)
    wrapper.normalizeD(Exp1_R25_pept[1:1000], "Median Centering", "within conditions")

[Package DAPAR version 1.10.4 Index]