# Time Series Clustering of Gene Expression with Gaussian Mixed-Effects Models and Smoothing Splines

## Documentation for package ‘TMixClust’ version 1.0.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

TMixClust-package | The main usages of TMixClust
analyse_stability | Stability analysis, clustering evaluation and optimal solution selection
best_clust_toy_obj | TMixClust object containing the optimal clustering solution for the toy data with 3 clusters.
best_clust_yeast_obj | TMixClust object containing the optimal clustering solution for the yeast data.
generate_TMixClust_report | Generates a series of files containing a summary of the TMixClust analysis results
get_time_series_df | Extracts a time series data frame from a text file
get_time_series_df_bio | Extracts a time series data frame from a Bioconductor Biobase ExpressionSet object.
plot_silhouette | Generates a silhouette plot for a given clustering configuration.
plot_time_series_df | Plots all the time series stored in a data frame object
TMixClust | Clusters the time series data in a given number of groups
toy_data_df | Simulated time-series gene expression data