f45cbmk {ProData} | R Documentation |
The data consist of 167 SELDI-TOF spectra from either individuals
with breast cancer or without (normal controls). Two covariates
are available. The data have been pre-processed by Ciphergen's
software and the specific details are as follows. The baselines
of the spectra were subtracted using the default parameter
settings of the Ciphergen software, and the spectra were
normalized by the total ion current normalization function of
the Ciphergen software. Peaks were detected with signal to noise
ratio (S/N) above 10. Proto-biomarkers, i.e., peaks in each
spectrum that have the same M/Z value, were detected with the
following parameters: first pass, 10 S/N, min peak threshold
10
pass, 5 S/N, and add estimated peaks to complete clusters and
it is the jointly normalized data that are available here.
The data are presented in the form of an exprSet
object.
data(f45cbmk)
The different covariates are:
Alex Miron's Lab at the Dana-Farber Cancer Institute.
Shi, Q. et al. Biomarker Discovery in Plasma Using Proteomics Ana lysis for Early Detection of Breast Cancer. 2004, manuscript.
data(f45cbmk)